Mermaid Central Medical Clinic Research

Sharing research in Long COVID, POTS, fibromyalgia and other areas

GABA dysfunction in POTS, Long COVID, Fibromyalgia and Long COVID

Graham Exelby

13 min read

GABA dysfunction in POTS, Long COVID, Fibromyalgia and Long COVID

Dr Graham Exelby December 2024 Abstract GABA (γ-aminobutyric acid), the primary inhibitory neurotransmitter in the central nervous...

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Sensitization in POTS, Long COVID and Fibromyalgia

Graham Exelby

29 min read

Sensitization in POTS, Long COVID and Fibromyalgia

Dr Graham Exelby December 2024 Abstract Central sensitization, characterized by increased responsiveness of the central nervous system...

113 views0 comments

Graham Exelby

4 min read

Heat and Cold Intolerance

Dr Graham Exelby December 2024 Temperature intolerance is a common symptom in Postural Orthostatic Tachycardia Syndrome (POTS) and often...

62 views0 comments

Targeting the Perfect Storm- Amino Acid Dysfunction in Post Exertional Malaise-

Graham Exelby

25 min read

Targeting the Perfect Storm- Amino Acid Dysfunction in Post Exertional Malaise-

Dr Graham Exelby. December 2024, revised February 2025 Introduction Post-exertional malaise (PEM) represents a multifactorial challenge...

208 views0 comments

Graham Exelby

21 min read

References for Brainstem Hypoperfusion, Coat Hanger Pain and PEM.

Graham Exelby September 2024 References: 1. Hira, R et al. Objective Hemodynamic Cardiovascular Autonomic Abnormalities in...

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Brainstem Hypoperfusion, Coat hanger pain and Post-Exertional Malaise in POTS and Long COVID

Graham Exelby

61 min read

Brainstem Hypoperfusion, Coat hanger pain and Post-Exertional Malaise in POTS and Long COVID

Dr Graham Exelby September 2024 Brainstem hypoperfusion, coat hanger pain and PEM have similar pathogenesis, and are found in that same...

487 views1 comment

Mould, Sustained Stress and PTSD in Immune Dysregulation

Graham Exelby

35 min read

Mould, Sustained Stress and PTSD in Immune Dysregulation

Dr Graham Exelby September 2024 In the complex pathophysiology that lies beneath POTS, Fibromyalgia and their comorbidities, persistent...

109 views0 comments

Amino Acid, Essential Vitamin and Mineral Burn off in Post Exertional Malaise

Graham Exelby

62 min read

Amino Acid, Essential Vitamin and Mineral Burn off in Post Exertional Malaise

A Preliminary Study -September 2024, currently being peer-reviewed Dr Graham Exelby Brainstem hypoperfusion, coat hanger pain and PEM...

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Management of Fibromyalgia and Co-Morbidities

Graham Exelby

31 min read

Management of Fibromyalgia and Co-Morbidities

Dr Graham Exelby February 2024 Introduction This article on management is based extensively on hundreds of face to face consultations in...

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Graham Exelby

13 min read

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-References

1. Overlapping Conditions. American Myalgia Encephalomyelitis and Chronic Fatigue Syndrome Society. https://ammes.org/overlapping-con...

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Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome- Part 1

Graham Exelby

26 min read

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome- Part 1

Dr Graham Exelby February 2024 The large quantity of data with images is more than this website will allow in 1 document, so it has been...

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Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 2

Graham Exelby

18 min read

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 2

Dr Graham Exelby February 2024 Intracranial Hypertension -linking CFS, POTS and Fibromyalgia Researchers such as Hulens et al (6) are...

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Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 3

Graham Exelby

12 min read

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 3

Dr Graham Exelby February 2024 Lymphatic connection Boisserand et al (74) confirmed in mice studies that “vertebral lymph vessels connect...

35 views0 comments

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 4

Graham Exelby

21 min read

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 4

Dr Graham Exelby February 2024 Looking at other research areas 1. Vagal Activity and Baroreceptors Bonaz et al (106) describe: “The...

29 views0 comments

Intra-Abdominal Vascular Compression Syndromes

Graham Exelby

18 min read

Intra-Abdominal Vascular Compression Syndromes

Dr Graham Exelby January 2024 Looking closely at causes for autonomic dysfunction, there are quite a number of areas where compression of...

192 views0 comments

Internal Jugular Vein Dysfunction- Jugular Outlet Syndrome, Internal Jugular Vein Stenosis and Obstruction

Graham Exelby

39 min read

Internal Jugular Vein Dysfunction- Jugular Outlet Syndrome, Internal Jugular Vein Stenosis and Obstruction

Dr Graham Exelby January 2024 Many of the typical symptoms associated with Postural Orthostatic Tachycardia Syndrome (POTS,)...

269 views0 comments

Intracranial Hypertension, Intracranial Hypotension and Craniovascular Pressure Change

Graham Exelby

51 min read

Intracranial Hypertension, Intracranial Hypotension and Craniovascular Pressure Change

Dr Graham Exelby. January 2024 This section is currently being revised to incorporate evolving information about the newly discovered CSF...

177 views0 comments

Graham Exelby

33 min read

The Glymphatic System

Glymphatic System (or glymphatic clearance pathway or paravascular system) Dr Graham Exelby. January 2024- Currently under revision...

196 views0 comments

Cervical Spine Abnormality, Ehlers-Danlos Syndrome and Vertebral Vascular and Lymphatic Dysfunction

Graham Exelby

50 min read

Cervical Spine Abnormality, Ehlers-Danlos Syndrome and Vertebral Vascular and Lymphatic Dysfunction

Dr Graham Exelby December 2023 This section is currently being revised to incorporate evolving information about the newly discovered CSF...

168 views0 comments

Graham Exelby

6 min read

Low Glutamate Diet

December 2023 Dr Graham Exelby, Dr Valerio Vittone, Ms Kelley Bright Diet change can be extremely important managing the inflammatory...

230 views0 comments

Articles Categories

Articles List

GABA dysfunction in POTS, Long COVID, Fibromyalgia and Long COVID

Sensitization in POTS, Long COVID and Fibromyalgia

Lymphatic and CSF Canalicular Systems

POTS- A Unifying Hypothesis

Assembling the Pieces of POTS

Heat and Cold Intolerance

Targeting the Perfect Storm- Amino Acid Dysfunction in Post Exertional Malaise-

Endometriosis -linked by pelvic congestion, and DNA mutations in TLR4 and COMT?.

References for Brainstem Hypoperfusion, Coat Hanger Pain and PEM.

Brainstem Hypoperfusion, Coat hanger pain and Post-Exertional Malaise in POTS and Long COVID

Mould, Sustained Stress and PTSD in Immune Dysregulation

Intracranial Hypertension- the Link betweenVascular and CSF Dysfunction

Amino Acid, Essential Vitamin and Mineral Burn off in Post Exertional Malaise

The Genetic Basis to Improving Toxin Detoxification

Long COVID Immune Dysfunction

Management of Long COVID Cognitive Impairment

Causes of Long COVID Cognitive Impairment

Breaking Through in POTS and Long Covid

Management of Fibromyalgia and Co-Morbidities

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-References

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome- Part 1

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 2

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 3

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 4

Intra-Abdominal Vascular Compression Syndromes

Internal Jugular Vein Dysfunction- Jugular Outlet Syndrome, Internal Jugular Vein Stenosis and Obstruction

Intracranial Hypertension, Intracranial Hypotension and Craniovascular Pressure Change

The Glymphatic System

Cervical Spine Abnormality, Ehlers-Danlos Syndrome and Vertebral Vascular and Lymphatic Dysfunction

Low Glutamate Diet

Managing POTS

DNA Mutations that Underpin POTS and Long Covid

QT Prolongation

Heart Rate Variability

DNA Mutations in POTS and Long Covid-Practitioner version MCAS Conference- April 2 2023-

DNA Mutations in POTS and Long Covid- Patient version-MCAS Conference- April 2 2023

Nigella Sativa in COVID

Nicotinamide Mononucleotide (NMN)

Low Dose Naltrexone, Ketotifen and other Mast Cell Treatments

Thoracic Outlet Syndrome (incorporating Costoclavicular Syndrome)

Migraine

A 50 Year Journey in Medicine

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Mermaid Central Medical Clinic Research Sharing research in Long COVID, POTS, fibromyalgia and other areas

GABA dysfunction in POTS, Long COVID, Fibromyalgia and Long COVID

Sensitization in POTS, Long COVID and Fibromyalgia

Heat and Cold Intolerance

Targeting the Perfect Storm- Amino Acid Dysfunction in Post Exertional Malaise-

References for Brainstem Hypoperfusion, Coat Hanger Pain and PEM.

Brainstem Hypoperfusion, Coat hanger pain and Post-Exertional Malaise in POTS and Long COVID

Mould, Sustained Stress and PTSD in Immune Dysregulation

Amino Acid, Essential Vitamin and Mineral Burn off in Post Exertional Malaise

Management of Fibromyalgia and Co-Morbidities

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-References

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome- Part 1

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 2

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 3

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 4

Intra-Abdominal Vascular Compression Syndromes

Internal Jugular Vein Dysfunction- Jugular Outlet Syndrome, Internal Jugular Vein Stenosis and Obstruction

Intracranial Hypertension, Intracranial Hypotension and Craniovascular Pressure Change

The Glymphatic System

Cervical Spine Abnormality, Ehlers-Danlos Syndrome and Vertebral Vascular and Lymphatic Dysfunction

Low Glutamate Diet

Articles Categories

Articles List

GABA dysfunction in POTS, Long COVID, Fibromyalgia and Long COVID

Sensitization in POTS, Long COVID and Fibromyalgia

Lymphatic and CSF Canalicular Systems

POTS- A Unifying Hypothesis

Assembling the Pieces of POTS

Heat and Cold Intolerance

Targeting the Perfect Storm- Amino Acid Dysfunction in Post Exertional Malaise-

Endometriosis -linked by pelvic congestion, and DNA mutations in TLR4 and COMT?.

References for Brainstem Hypoperfusion, Coat Hanger Pain and PEM.

Brainstem Hypoperfusion, Coat hanger pain and Post-Exertional Malaise in POTS and Long COVID

Mould, Sustained Stress and PTSD in Immune Dysregulation

Intracranial Hypertension- the Link betweenVascular and CSF Dysfunction

Amino Acid, Essential Vitamin and Mineral Burn off in Post Exertional Malaise

The Genetic Basis to Improving Toxin Detoxification

Long COVID Immune Dysfunction

Management of Long COVID Cognitive Impairment

Causes of Long COVID Cognitive Impairment

Breaking Through in POTS and Long Covid

Management of Fibromyalgia and Co-Morbidities

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-References

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome- Part 1

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 2

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 3

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 4

Intra-Abdominal Vascular Compression Syndromes

Internal Jugular Vein Dysfunction- Jugular Outlet Syndrome, Internal Jugular Vein Stenosis and Obstruction

Intracranial Hypertension, Intracranial Hypotension and Craniovascular Pressure Change

The Glymphatic System

Cervical Spine Abnormality, Ehlers-Danlos Syndrome and Vertebral Vascular and Lymphatic Dysfunction

Low Glutamate Diet

Managing POTS

DNA Mutations that Underpin POTS and Long Covid

QT Prolongation

Heart Rate Variability

DNA Mutations in POTS and Long Covid-Practitioner version MCAS Conference- April 2 2023-

DNA Mutations in POTS and Long Covid- Patient version-MCAS Conference- April 2 2023

Nigella Sativa in COVID

Nicotinamide Mononucleotide (NMN)

Low Dose Naltrexone, Ketotifen and other Mast Cell Treatments

Thoracic Outlet Syndrome (incorporating Costoclavicular Syndrome)

Migraine

A 50 Year Journey in Medicine

Mermaid Central Medical Clinic Research

Sharing research in Long COVID, POTS, fibromyalgia and other areas