
GABA dysfunction in POTS, Long COVID, Fibromyalgia and Long COVID
Dr Graham Exelby December 2024 Abstract GABA (γ-aminobutyric acid), the primary inhibitory neurotransmitter in the central nervous...
Graham Exelby
13 min read
489 views
1 comment

Sensitization in POTS, Long COVID and Fibromyalgia
Dr Graham Exelby December 2024 Abstract Central sensitization, characterized by increased responsiveness of the central nervous system...
Graham Exelby
29 min read
138 views
0 comments
Heat and Cold Intolerance
Dr Graham Exelby December 2024 Temperature intolerance is a common symptom in Postural Orthostatic Tachycardia Syndrome (POTS) and often...
Graham Exelby
4 min read
72 views
0 comments

Targeting the Perfect Storm- Amino Acid Dysfunction in Post Exertional Malaise-
Dr Graham Exelby. December 2024, revised February 2025 Introduction Post-exertional malaise (PEM) represents a multifactorial challenge...
Graham Exelby
25 min read
302 views
0 comments
References for Brainstem Hypoperfusion, Coat Hanger Pain and PEM.
Graham Exelby September 2024 References: 1. Hira, R et al. Objective Hemodynamic Cardiovascular Autonomic Abnormalities in...
Graham Exelby
21 min read
105 views
0 comments

Brainstem Hypoperfusion, Coat hanger pain and Post-Exertional Malaise in POTS and Long COVID
Dr Graham Exelby September 2024 Brainstem hypoperfusion, coat hanger pain and PEM have similar pathogenesis, and are found in that same...
Graham Exelby
61 min read
504 views
1 comment

Mould, Sustained Stress and PTSD in Immune Dysregulation
Dr Graham Exelby September 2024 In the complex pathophysiology that lies beneath POTS, Fibromyalgia and their comorbidities, persistent...
Graham Exelby
35 min read
114 views
0 comments

Amino Acid, Essential Vitamin and Mineral Burn off in Post Exertional Malaise
A Preliminary Study -September 2024, currently being peer-reviewed Dr Graham Exelby Brainstem hypoperfusion, coat hanger pain and PEM...
Graham Exelby
62 min read
253 views
0 comments

Breaking Through in POTS and Long Covid
Revised December 2024 This section is currently being revised to incorporate evolving information about the importance of fascial...
Graham Exelby
10 min read
341 views
0 comments

Management of Fibromyalgia and Co-Morbidities
Dr Graham Exelby February 2024 Introduction This article on management is based extensively on hundreds of face to face consultations in...
Graham Exelby
31 min read
327 views
0 comments
Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-References
1. Overlapping Conditions. American Myalgia Encephalomyelitis and Chronic Fatigue Syndrome Society. https://ammes.org/overlapping-con...
Graham Exelby
13 min read
67 views
0 comments

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome- Part 1
Dr Graham Exelby February 2024 The large quantity of data with images is more than this website will allow in 1 document, so it has been...
Graham Exelby
26 min read
375 views
0 comments

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 2
Dr Graham Exelby February 2024 Intracranial Hypertension -linking CFS, POTS and Fibromyalgia Researchers such as Hulens et al (6) are...
Graham Exelby
18 min read
66 views
0 comments

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 3
Dr Graham Exelby February 2024 Lymphatic connection Boisserand et al (74) confirmed in mice studies that “vertebral lymph vessels connect...
Graham Exelby
12 min read
38 views
0 comments

Fibromyalgia Syndrome and the Linking with POTS and Chronic Fatigue Syndrome-Part 4
Dr Graham Exelby February 2024 Looking at other research areas 1. Vagal Activity and Baroreceptors Bonaz et al (106) describe: “The...
Graham Exelby
21 min read
32 views
0 comments

Intra-Abdominal Vascular Compression Syndromes
Dr Graham Exelby January 2024 Looking closely at causes for autonomic dysfunction, there are quite a number of areas where compression of...
Graham Exelby
18 min read
210 views
0 comments

Internal Jugular Vein Dysfunction- Jugular Outlet Syndrome, Internal Jugular Vein Stenosis and Obstruction
Dr Graham Exelby January 2024 Many of the typical symptoms associated with Postural Orthostatic Tachycardia Syndrome (POTS,)...
Graham Exelby
39 min read
304 views
0 comments

Intracranial Hypertension, Intracranial Hypotension and Craniovascular Pressure Change
Dr Graham Exelby. January 2024 This section is currently being revised to incorporate evolving information about the newly discovered CSF...
Graham Exelby
51 min read
179 views
0 comments

The Glymphatic System
Glymphatic System (or glymphatic clearance pathway or paravascular system) Dr Graham Exelby. January 2024- Currently under revision...
Graham Exelby
33 min read
219 views
0 comments

Cervical Spine Abnormality, Ehlers-Danlos Syndrome and Vertebral Vascular and Lymphatic Dysfunction
Dr Graham Exelby December 2023 This section is currently being revised to incorporate evolving information about the newly discovered CSF...
Graham Exelby
50 min read
173 views
0 comments